Question: Mutect 2 and related vcf in TCGA
There are 1 vcf file from the DNA sequencing available in GDC: tumor/normal. I'm a little confused about the presence of the normal SNV in this file. Is this file containing the somatic SNVs in the normal sample? why there are no SNVs with an allelic frequency>0 in the normal but =0 in the tumor?
• 1,653 views
•
link
written
by
salvatore.digiorgio •
0 answers
No answers yet.
Log in to answer this question.
More posts like this
-
Somatic SNVs vs. Germline SNPs for allele-specific copy number analysis
written by vctrm67 •
-
Understanding TCGA somatic mutation files
written by j.lunger18 •
-
Some clarification on Strelka output
written by zizigolu
-
Annovar result GT field
written by vaish01kv •
-
the difference between the positions called by somatic caller (MuTect2) and the position called by …
written by Zoey Zou •
-
Can anyone help me to confirm the number of matched tumor and normal samples in TCGA-BRCA?
written by Wen Wang •
-
Strelka output: read count of REF and ALT, SNVs
written by noeD
-
When can I distinguish between an SNV and a sequencing error?
written by Gene_MMP8
-
Understanding SomaticSniper output
written by ttom
-
Tool: Somaticsniper - Variant Caller Used For Somatic Snvs And Indels
written by Malachi Griffith
