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Does it make sense to use genomes of healthy centenarians as the reference genome?

Does it make sense to use genomes of healthy centenarians as the reference genome?

Is there any public genomes of healthy centenarians?

sequencing genome

healthy centenarians

Per what criteria. Just because they they made it to 100?

What's the purpose of the "reference genome"? For what is it the reference? You need to add more information about the aim of your analysis.

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