Hi, I have an OTU table (not 16S data but WGS data from illumina). This table does not come from qiime. It´s a custom pipeline based on the taxonomy assignment using single copy genes (not 16S markers).

I have build my OTU table i would like to compare samples using unifrac distances for example. I don´t have a tree (neither sequence alignment as i have used single copy genes to derive taxonomy) so i was wondering what would be the best way to proceed if possible ??

Thanks, david