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liftOver narrowPeak file

I am wondering how you can use liftOver to convert mm10 narrowPeak files back to mm9? Thanks.

liftover assembly

Just curious if you've ever figured this out. I'm wondering the same for GRCh38-mapped narrowPeak files to hg19. I suspect getting rid of the offending columns is not advisable.

Just curious have you figured this out?

1 answer

I just stumbled upon this problem, and it turns out the solution is very easy:

liftOver \
-bedPlus=6 \
sample.narrowPeak.gz \
mm10Tomm9.over.chain.gz \
sample.lifted.narrowPeak \
sample.unmapped.narrowPeak

The important line here is -bedPlus=6. This will treat only the first 6 columns in your input file as a BED file. The rest of the columns will just be "carried along for the ride".

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