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filter my exome vcf files

well Im back with silly questions..

Is there any easy guide to understand how to filter my vcf files? I have exome secuency, I filtered my vcf file just to have SNPS and exclude QD<2 (I need to start somewhere) eventhought still I have over 35.000 genes (too many for my brain to study)

Got QUAL from 100-3000 If Im not wrong higher better (but which I can discard...under 1000...800....??

In my vcf head file have many different values of:

 [1]CHROM   [2]POS  [3]REF  [4]ALT  [5]QUAL [6]GENE [7]GT   [8]GQ   [9]FILTER   [10]AF  [11]AO  [12]BKPTID  [13]CDF_LD  [14]CDF_MAPD    [15]CIEND   [16]CIPOS   [17]CONFIDENCE  [18]DP  [19]END [20]FAO [21]FDP [22]FR  [23]FRO [24]FSAF    [25]FSAR    [26]FSRF    [27]FSRR    [28]FWDB    [29]FXX [30]HOMLEN  [31]HOMSEQ  [32]HRUN    [33]HS  [34]LEN [35]MEINFO  [36]MLLD    [37]NS  [38]NUMTILES    [39]OALT    [40]OID [41]OMAPALT [42]OPOS    [43]OREF    [44]PRECISE [45]PRECISION   [46]QD  [47]RBI [48]REFB    [49]REVB    [50]RO  [51]SAF [52]SAR [53]SRF [54]SRR [55]SSEN    [56]SSEP    [57]SSSB    [58]STB [59]STBP    [60]SVLEN   [61]SVTYPE  [62]TYPE    [63]VARB    [64]FUNC    [65]SF

If anyone can provide a link where I can learn easily how to reduce my vcf file I would really appreciate it.

Thanks

filter vcf file

Thanks Fabio, I hadnt done this vcf files, my pc sadly cant handle to do that kind of jobb (I tried once and was a hell). Just got this vcf done by a company. And I dont think they used Gatk, they have their own program.

Thanks for the link.

easily how to reduce my vcf file

That highly depends on what the aim of your analysis is. Looking for a causal variant, an eQTL study, population genetics,...

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