Chip Seq controls
Hello All,
I am presently working with breast cancer chip seq data housed in EBI for a variety of transcription factors. When I run MACS2 peak caller without control , I find some random peaks where are no where close to gene promoters.I was looking for control files for the experiments, but till now did not succeed.Any suggestions. Thanks in advance.
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You could use blacklists from ENCODE/modENCODE to remove false peaks that overlap blacklisted coordinates.
Have you checked GEO or ArrayExpress to find input for the tissue you are investigating.
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