When I find genes from Flybase, some genes have a couple isoforms (transcript variants). I wonder how they are generated. Alternative splicing or alternative promoter? For example, I searched a MDR49 gene and there are two different isoforms. They are generated by alternative splicing or alternative promoter?
Thanks!!
•
written
by
skmook16 •
1 answer
See this link:
http://flybase.org/static_pages/newhelp/gbrowse_geneModels_evidence_help.html
and "allows prediction of alternatively spliced isoforms" in it.
The whole paragraph:
"NCBI gnomon Gene prediction (coding region of transcript) generated via a hidden Markov model using transcript alignment constraints and protein hit information, if available; allows prediction of alternatively spliced isoforms (Souvorov, et al., 2006, NCBI); submitted by J. Ostell. "
http://flybase.org/reports/FBgn0259246.html
In the upper right corner replace :"Jump to gene" to your preferred gene-name and press GO:
You will get this page:
http://flybase.org/reports/FBgn0004512.html
Again on the left you can play with "gene region": intron, exons, etc.
Log in to answer this question.
-
Different annotations for different isoforms from the same gene
written by Chikae •
-
Ensembl transcript IDs
written by arsala521 •
-
Question for Splice variants and Alternative splicing
written by umeshtanwar2 •
-
Compare expression level of isoforms among conditions - TPM or deseq2 normalised counts?
written by tianshenbio
-
Get accumulated gene expression from alternative splicing in DESeq2
written by bharata1803
-
Tools for alternative splicing of distant genes
written by User 7754
-
Summary of alternative splicing from Cufflinks
written by Daniel Standage
-
Alternative splicing analysis, rna-seq
written by marina-orlova
-
Ngs Data V.S Microarray Data
written by jack •
-
Are Novel Junctions Only Give Novel Transcripts?
written by Ngsnewbie •
