Chip-seq Binding sites
Where can i find chip-seq peak files except ENCODE for various Transcription factors in various cell lines(e.g. i am looking CTCF with MCF7 binding sites)? Iam looking for files with hundreds or thousands of genes.
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Denise CS
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atsalaki •
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atsalaki •
1 answer
Check the Ensembl Regulatory Build. You will find Roadmap and Blueprint there, besides ENCODE. Check one of the Ensembl blog posts on the addition of Blueprint data.
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See these articles:
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2940-7
Motif oriented high-resolution analysis of ChIP-seq data reveals the topological order of CTCF and cohesin proteins on DNA
http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-15-80
Application of experimentally verified transcription factor binding sites models for computational analysis of ChIP-Seq data
http://tools.thermofisher.com/content/sfs/brochures/ChipSeq-Application-Note-CO28266.pdf
but note,
"Genomic binding sites for CTCF, H3K27ac, and H3K27me3 identified in K-562 cells using the MAGnify ™ Chromatin Immunoprecipitation System and the Ion Proton ™ System were compared to ENCODE project results "