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easiest way to perform homologue gene conversion

Actually I have a very large gene set of worm and I am trying to homologue it to human or mouse. I know already two online web base that do this but they are not working well and probably not anymore used or updated.

Any suggestion? if you have any solution with any programming language , please share

Thanks

genomics
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updated by Sej Modha Sej Modha • written by Learner Learner

1 answer

You could try Ensembl Compara

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written by Sej Modha Sej Modha

@Sej Mocha do you know how to use it for my purpose ? because I have never used it

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written by Learner Learner

You can use ensembl api (link above) that explains in detail how to install the api and also has multiple examples of various methods integrated in ensembl api. You can also check out EBI website for the video tutorials.

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written by Sej Modha Sej Modha

@Sej Mocha thanks I checked it out, this is definitely a pain and it is absolutely not user friendly and more importantly out of date , over 5 years no one touch this !!! how can I trust the annotation ?

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written by Learner Learner

Did you know that Ensembl databases are updated regularly up to 4 times a year. New annotations and genome builds are added/updated in each release. It is a really useful resource. Check out the latest release - July 2016

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written by Sej Modha Sej Modha

@Sej Mocha oh I was not aware of this!!!!! I think you very much for giving me the chance to see it is updated , so I can trust it though. !!!!

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written by Learner Learner

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