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Compare two sets of sequences generating similar PWM (logos)

Hi,

I have two sets of sequences I want to check if they contain similar motifs. I have generated PWM logos with both sets and results are similar but I would like to apply some statistical test that actually describe motif occurrence similarity between both sets.

Thanks in advance!

sequence motifs pwm logo

1 answer

You can use meme: http://meme-suite.org/tools/meme It has a web version but you can also download the command line tool.

The TomTom tool from the same suite as MEME handles motif comparison.

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