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UCSC Xena CNV GISTIC2 (Threshold)

If I use the data from the link below "TCGA colon adenocarcinoma (COAD) copy number gistic2_thresholded estimate".

https://genome-cancer.soe.ucsc.edu/proj/site/xena/datapages/?dataset=TCGA.COAD.sampleMap/Gistic2_CopyNumber_Gistic2_all_thresholded.by_genes&host=https://tcga.xenahubs.net

How can I calculate the significance of Amplification/deletion of each gene? Or is it possible to calculate the significance of Amplification/deletion?

cnv tcga gistic2

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