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Is there an integrated way to analyse mutation data and protein expression data

Hi, I have two types of data, say: 1) genome wide DNA mutation data by next-gen sequencing. 2) several protein expression data from the same sample by immunohistochemical analysis Is there a best way (suitable r package) to analyse these data?

Thanks

next-gen mutation immunohistochemistry
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written by ShirleyDai • ShirleyDai

Answers to these will help determine how best to approach the data analysis.

  • What question do you want to answer with your data?
  • Is the information from IHC quantitative, or just qualitative (present/absent)?
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written by Sean Davis Sean Davis

My hypothesis is the differences of mutation load exist between high expression marker and low expression marker. My IHC data was classified qualitatively as high or low.

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written by ShirleyDai • ShirleyDai

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