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Postdoctoral Fellow in Computational Toxicology, Bioinformatics Institute, Singapore
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3.9 years ago


A postdoctoral research fellow position in the area of computational toxicology is available in the Loo lab ( , A*STAR, Singapore. The group is interested in studying chemical-induced toxicity using quantitative data modeling and cellular imaging methods. The group has recently developed the first high-throughput cellular imaging and computational platform for predicting kidney toxicity.

The successful candidate will be part of an interdisciplinary team that develops novel in vitro and computational models for predicting the toxicity of drugs, food ingredients, industrial chemicals, and environmental pollutants. He/she will develop new computational methods to analyze and model cellular responses based on chemical structures, cellular phenotypes, and gene and protein expression profiles. The candidate will have the opportunity to work in a highly stimulating environment, and participate in the global effort to develop next-generation and animal-free technologies for Toxicity Testing in the 21st Century (TT21C).


Candidates must have a strong quantitative background, with a Ph.D. in either computational biology, chemical engineering, chemistry, toxicology, pharmacology, computer science, bioengineering, or other related fields. Strong knowledge in machine learning, data mining, regression analysis, statistics, and programming (R and/or Python) are required. Candidates with previous experience in cheminformatics, bioinformatics, QSAR modeling, virtual screening, or PBPK modeling are especially encouraged to apply. Candidates must also possess good communication skills, and be fluent in both spoken and written English.

About BII:

The Bioinformatics Institute (BII), Agency for Science and Technology Research (ASTAR), focuses on theoretical approaches aimed at understanding biomolecular mechanisms that underlie biological phenomena, the development of computational methods to support this discovery process, and experimental verification of predicted molecular and cellular functions of genes and proteins with biochemical methods. Together with the other ASTAR research institutes and multinational R&D organizations in the Biopolis, the BII is situated in a conducive environment for exchange of scientific knowledge and friendly interaction that will prompt greater collaborations, and position the Biopolis as a notable biomedical R&D hub in Asia and in the world.

Application Procedures:

Applicants should send

  1. a one-page cover letter briefly describing prior research experience and accomplishments,
  2. a one-page statement of research interests,
  3. CV,
  4. contact information of two references, and
  5. reprints of one to two publications

to Dr. Lit-Hsin Loo (


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