If I have a inteseted bacteral protein geneor it from pathogene, is there a way that I can find homogeneous protein in human through database searching?
or its related proteins ... The protein we are targeting is gtfb that we study it's binding/ adhesion properties.
Thank you so much! Ivy
• 2,216 views
•
link
updated
by
natasha.sernova
•
written
by
Ivy Ng •
•
written
by
Ivy Ng •
0 answers
No answers yet.
Log in to answer this question.
More posts like this
-
How to predict the affinity between Protein and RNA?
written by Alex •
-
Do monoclonal antibodies have a blocking effect?
written by jinyu •
-
Package suggestion to calculate Protein-Protein interaction.
written by UGUR •
-
Stability and binding affinity of the complex upon mutation
written by aupris •
-
Docking in small sized ribosomal protein
written by AjArathi •
-
Interpreting ChIP-qPCR or ChIP-seq
written by panagiotix •
-
What's the difference between Biological process and pathway when analyzing group of protein under …
written by Ivy Ng •
-
Maestro (Schrodinger Software), Protein Data Bank,
written by Ready2Rapture •
-
How to predict cancer-related proteins in Protein-Protein Interaction networks
written by txd866 •
-
Searching For Proteins That Have Similar Type Of Residues In Binding Pocket
written by Flow
As far as I have understood, you have some bacterial genes and
you would like to determine if they have some human homologs, am I correct?
This is one of the comprehensive human gene databases:
http://www.ncbi.nlm.nih.gov/genome/guide/human/
This post is close to your question to some extent:
How To Find Human And Bacteria Homologs Of S. Pombe Protein.
At least, it discusses ENSEMBLE database.
Many years ago scientists showed the following:
Homologous ribosomal proteins in bacteria, yeast, and humans.
http://www.ncbi.nlm.nih.gov/pubmed/3529092
You can try to do something similar, if you replace Drosofila genes to your bacterium genes.
See this post. Human latest genome release has been updated since then.
Identifying Homologues In Drosophila For Human Genes On Large Scale
Thank you so much, it's really helpful!