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How to classify cancer genes as oncogene & tumor suppressor gene?

I have a list of genes, which are possibly cancer causing genes, how can i classify them as oncogene or tumor suppressor gene? Based on what, genes can be classified as oncogene and tumor suppressor gene?

gene oncogene tumour suppressor gene software
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updated by Obi Griffith Obi Griffith • written by Pranavathiyani G Pranavathiyani G

1 answer

A very similar question was asked previously: Database Of Tumor Suppressors And/Or Oncogenes

This paper also addressed the topic and provides a method based on mutation data: http://www.ncbi.nlm.nih.gov/pubmed/26209800

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written by Obi Griffith Obi Griffith

I would add the 20/20 rule introduced by Vogelstein in 2013, which I think was the first formal definition of a rule to determine tumor suppressors and oncogenes.

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written by Giovanni M Dall'Olio Giovanni M Dall'Olio

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