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GC content calculation for Genes

I have a list of Human Genes(Gene Symbols: E.g.,-> PTEN, AASS, AATBC, AATF, QARS, ABAT, ACHE, etc), How can I find the GC content(%) of these genes? Is there any tool or database available?

I don't want to calculate by taking each gene sequence & to find the GC content. Is there any alternative way, a tool?

database gene cpg sequence
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updated by Ram Ram • written by Pranavathiyani G Pranavathiyani G

I think that throughout the gene body and exon intron structure your GC value will differ widely and as such a GC content per gene will be a meaningless trait... perhaps (depending on what you want to do) a sliding window approach is more appropriate.

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written by WouterDeCoster WouterDeCoster

This is hugely important. You really need to be sure that the term "gene" is meaningful given the context of your experiment. Fortunately, that link Devon gave you makes it really easy to slice and dice your regions with the filters :)

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written by John John

2 answers

Because I'm nice, here is the biomart URL with the result for all human genes.

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written by Devon Ryan Devon Ryan

You can get %GC from Biomart.

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written by mastal511 mastal511

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