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450k Methylation and Translocation

This is possible to identify translocation form 450k Methylation data ? Can anyone please explain why or why not this is possible ? Thanks !!

methylation translocation
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updated by Devon Ryan Devon Ryan • written by Tanvir Ahamed Tanvir Ahamed

1 answer

There's no way for a 450K methylation array to measure if signal happens to be from a translocated region or not. You'd need a completely different array to look at that, one designed specifically to look for translocations (it'd make more sense to just sequence to low depth).

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written by Devon Ryan Devon Ryan

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