Hi all,
I have an alignment in fasta format and a phylogenetic tree in Newick format. I am looking for a way to visualise/map the character state changes or SNPs to the node/branches they define. Any suggestions on available software that does this?
Thanks in advance, Tim.
2 answers
What organism are you working with?
In case of bacteria, there several tools and papers about them:
PhyTB: Phylogenetic tree visualisation and sample positioning for M. tuberculosis
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429496/
Displaying data associated with phylogenetic trees - there is a comparison of many tools
https://bacpathgenomics.wordpress.com/2012/05/25/displaying-data-associated-with-phylogenetic-trees/
Again bacteria:
http://nar.oxfordjournals.org/content/early/2016/04/29/nar.gkw359.full
In case of humans or viruses:
Whole genome single-nucleotide variation profile-based phylogenetictree building methods for analysis of viral, bacterial and human genomes
http://www.sciencedirect.com.sci-hub.cc/science/article/pii/S0888754314000949
or this one:
Population structure: GST, genetic distance, and clustering
http://grunwaldlab.github.io/Population_Genetics_in_R/Pop_Structure.html
Thank you heaps for that, it should help with my human mtDNA data!
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