Hello,

I have the quaternary structures of hetero-dimeric proteins. I am trying to separate the 2 chains of each protein complex and dock them. Prior to docking I have to randomize the side chain orientation of all amino acids in both the chains of each of the protein complexes to check the extent to which the docking process brings the orientation back to that present in the bound state of the protein complex.

Is there any software that can randomize the side chain orientations of all amino acids in a protein in a single command? Can this be done on GROMACS? Thank you in advance

Akash