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Tools to display mutations in a protein's structure

I want to graphically display a number of point mutations in a protein graphically. I am aware of protein-structure-predicting tools (https://en.wikipedia.org/wiki/List_of_protein_secondary_structure_prediction_programs) but I have not heard of any tools that exist for displaying multiple mutations on a single protein.

I would ideally like to great an interactive graphic that would allow the viewer to see each mutation's location highlighted on wild-type structure and be able to select one or more mutations then view their predicted impact on the protein's structure. But simply high-lighting the location of a list of mutations with a different color is my primary goal.

protein sequence

2 answers

cbioportals mutationmapper has an option for this. Once you load your mutation data and submit, you can click on 3D structure for interactive 3D structure with mutations highlighted.

The Genomics 2 Proteins portal's Interactive Mapping module is designed for this purpose. You can upload sets of mutations or experimental readouts from a screen.

You can change colors, etc, map other features from other variant and feature databases, and export the final output to PyMOL as well.

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