Is there a simple and automated way to do a BLAST analysis of 900 genes to find clusters... or should I make a 900x900 table and compare each gene individually with each other?
OrthoMCL is another good choice in addition to CD-HIT as mentioned by Neilfws. Alternatively, you might want to use SiLiX which is very fast and could be used for both nucleotide sequences or amino acid sequences.
I have a set of eight clusters from a larger gene regulatory network consisting of transcription factors and the genes they regulate (bipartite network). The …