WGCNA module membership cutoff
Dear all,
It is my first time to work with WGCNA to investigate and compare co-expression networks of two organisms.
I want to use a cutoff to select genes with higher module-membership values. When I choose 0.8 or 0.7 as cutoff, I can only find very few biological meaningful genes in each module, but when I choose 0.6 the results are more satisfactory.
My question is: is there any criteria or limit for selecting module membership values?
is 0.6 very low cutoff for module membership values?
I will appreciate any advice
Regards
Nazanin
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What "cuttoff" are you talking about? do you mean he "kWithin" value returned by the intramodularConnectivity function?