how to choose hub genes in wgcna
hello, I am following this tutorial and calculated gene significance(GS) and inter-module connectivity of genes: module membership(MM). I came across some studies (example: 1, 2) where they used GS and MM cutoff to choose hub genes.
- can anyone suggest which method to use to select hub genes? and provide an R script for selecting hub genes based on GS and MM cutoff.
Thankyou
Parin
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This paper could help you regarding hub gene identification by R package (dhga) hub gene identification
Hi Parin
Check out similar posts on Biostars and see if that helps
Hub selection in WGCNA
How to find the hub genes in the gene co-expression network constructed by WGCNA
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