Chromosome specific sequencing approachs
Hi friends
When I read about Human genome project I confused, How the identified chromosomes' sequence content,map,...?
Actually, If we don't have enough information about chromosomes or in de-novo species,
How could we be able to sequence genomes? (and determine each Chr's sequence)?
Thanks from all of you.
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Are you asking how assembled sequences could be assigned to particular chromosomes? If so, have a look at FISH.
Flow sorting chromosomes? BAC libraries? Minimal tiling paths? I think perhaps reading the papers would illuminate your question
http://www.nature.com/nature/journal/v409/n6822/full/409860a0.html
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