Hi,
The problem is not the number of files but the number of effective "open" files. I did not look at the source code but it seems odd to me that all 8000+ files are "open". I am wondering if keeping all those files in "open" state is the intention of the program or if the programmer forgot to close some of the files after the processing is completed. This is the output I get from my run:
https://docs.google.com/document/d/1jpooJySV1rKTQEronzGyprgdSISPwdhcbBJSDOflR_4/edit?usp=sharing
total input file size is 28 GB (2 fastq files each 14GB)
Thanks
Best Regards
T. Hamdi Kitapci