A: comparing vcf files of disease (affected) and normal (unaffected) samples
Dear friends,
My requirement is to find list of variants which are present in affected but not in unaffected samples, then I have to prepare a list For example,
Samples 4:1243-SNV 5:1277-SNV 15:4070-SNV ….. ….. …… …… ….. ….. 16:5335-SNV
A(affected) C_T A_G A_T ….. ….. …… …… ….. ….. A_C
B(unaffected) C_C A_A A_A ….. ….. …… …… ….. ….. A_A
C(affected) C_T A_G A_T ….. ….. …… …… ….. ….. A_C
D(affected) C_T A_G A_T ….. ….. …… …… ….. ….. A_C
Any help friends.
I generated the vcf files using GATK tool.
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ramanandan.prabhakaran •
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ramanandan.prabhakaran •
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vcftools will be helpful in this case.
Thanks Ashutosh for your suggestion.