Hi, I work with nonhuman data. I have a bunch of SNPs that I want to predict how deleterious the SNP is. I know there …

Hi fellow members, I would like to get some explanation from those respected seniors who are experienced in the Bioinformatics analyses as i'm a newbie …

How should I interpret for example, SIFT score: SIFT_pred = T;T;T;T;D;T SIFT_score = 0.138;0.138;0.138;0.138;0.042;0.157 From dbNSFP documentation, I understand the meaning of D and T …

Hi, I am trying to figure out which tool VEP or Annovar, is most accurate in terms of SIFT and Polyphen annotation. I annotated my …

Because of splicing, one variant may affect different transcripts and the effect can be different from one transcript to another. In the case where there …

Dear all, I have a problem in understanding the exact meaning of FDR. I know it is the number of false positives divided by the …

Hi. I am wondering a term with SIFT score. I think that SIFT refers to some measurement of SNPs, and while reading Annovar paper, I …

<p>Hello All,</p> <p>I'm using annovar (which sometimes uses dbNSFP) for annotating variants against different databases, such as: SIFT, Polyphen2, Mutation Taster and etc</p> <p>Let's say …

<p>Hello,</p> <p>Does anyone know of any good algorithms for predicting the functional impact of indels? Similar in nature to SIFT, PolyPhen2, Panther, Mapp, etc. (however …

<p>Hi all,</p> <p>I'm looking for an explanation about the confidence threshold of CNVPartition. Does anyone know how is it calculated ? Is it intensity or …