software to caculate gene frequency based on SNP ped and map file
I had SNP-genotype (Illumina SNP-chip) data (ped and map files). Now I'd like to construct phylogeny tree with bootstrap support based on total 46 populations. I used the Phylip for the analysis, but how to use the ped and map files to calculate gene frequency as input for the Gendist for the population genetic distance?
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You can use plink --freq in conjunction with --keep to compute frequencies per-population. It will need to be re-formatted into the Gendist input, but there's not much more to do than paste
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