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Downloading fasta sequences for PDB IDs in bulk

Hello,

I have a list of 3000 pdb IDs, for which I need (1) fasta sequences from PDB and (2) Uniprot sequences. Is there a simpler way of downloading the sequences instead of manually downloading for each ID?

thanks in advance!

sequence
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updated by Ram Ram • written by amruta.biotech • amruta.biotech

3 answers

Lets say you have a txt file with pdb IDs:

2AID
4RLB

You can do something like:

parallel -a pdb_list.txt curl -o {}.fasta http://www.rcsb.org/pdb/files/fasta.txt?structureIdList={}

If you do not have parallel:

while read line; do curl -o ${line}.fasta http://www.rcsb.org/pdb/files/fasta.txt?structureIdList=${line}; done < pdb_list.txt

Try similar approach for Uniprot

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written by GouthamAtla GouthamAtla

No. Please do it from your terminal on Mac or Linux

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written by GouthamAtla GouthamAtla

The uniprot facility which I link to below is web-based and therefore works for any platform. The limit of number of IDs you can give (in a file) is in the 10s of thousands, so you shouldn't have a problem. If you do, contact uniprot help.

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updated by Ram Ram • written by sarahhunter sarahhunter

Have a look

http://seqanswers.com/forums/showthread.php?p=149802

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written by HG HG

Uniprot provides a facility to do bulk download through their website.

http://www.uniprot.org/uploadlists/

Through this feature you can get any sequence contained within the uniparc archive, including PDBseqs

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updated by Ram Ram • written by sarahhunter sarahhunter

Thanks,

Can you help me downloading the PDB fasta sequences if PDB IDs are submitted?

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written by amruta.biotech • amruta.biotech

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