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Where can I get the genelist in Oncoscan?

Hi all.

I want to use oncoscan for my research and Oncoscan is specially aimed at targeting hot spots regions for Cancer

I heard that there are several cancer related genes in oncoscan sites.

However, I cannot find the cancer genelist in oncoscan.

Does anybody know where they are?

genome alignment next-gen

1 answer

You can obtain a BED file of coordinates targeted by the Oncoscan assay here: http://www.affymetrix.com/estore/support/file_download.affx?onloadforward=/analysis/downloads/na33/genotyping/OncoScan.na33.r1.bed.zip

I believe you will be required to log in before you can download this file. You can intersect these coordinates with known gene/transcript annotations (e.g. using bedtools) to determine the identity of genes covered by the assay.

Or you could download the annotation file provided by Affy here: http://www.affymetrix.com/Auth/analysis/downloads/na33/genotyping/OncoScan.na33.r1.annot.csv.zip

More generally, here is a thread that covers others sources of cancer related genes: Database Of Tumor Suppressors And/Or Oncogenes

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