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Extracting features for mutated gene sequences

Hi,

I need to extract features from gene sequences for disease identification through machine learning techniques. Kindly help.

snp genome sequence gene

What kind of feature? What kind of data? Please provide more information

For missense/nonsense mutation data

My aim to identify disease from missense mutations based on machine learning algorithms.

So you are saying, you have a bunch of missense mutations and try to use machine learning algorithms to see if they are related to a particular disease?

If you have the case and control, then why don't you just use the statistic test to test the association?

So you are saying that you are having snps on multiple different sequences and are trying to see if certain nucleotide sequences can help you to predict the disease status?

As am using large number of sequences am in need to extract features to predict disease from gene sequences based on machine learning techniques.

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