Thanks for the response! Yeah, I think I got a little bit confused. Thanks for the suggestion on reading the beadArray package information (I've already read the lumi package information), it provided some key bits on information I was missing. So essentially, (specific to Illumina bead arrays), for each nuID (unique probe sequence), there are many replicate beads. In most cases there is one probe per gene, but in some cases there are more than one probe.
I guess this brings me on to a followup question.... If there are more than one probe for a given gene, is this to fill space on the array? Target potential transcript variants? Or are transcript variants not really accounted for because it's a gene level assay? I looked at a couple of genes in my data with more than one probe and they appeared to target the same exon but in slightly different locations.