Hi dear all,

I am working with two ChIP-seq data, one is input control, the other is TF IP.

I have the data in Bedgraph. MACS2 can use bedgraph as input for peak calling.

I used bdgcmp parameter for comparing the input and TF IP bedgraph for peak calling.

However, the program return this error: ERROR :Invalid method: i

My code is:

macs2 bdgcmp -c input.bedgraph -t TF_IP.bedgraph -o TF_IP_peak_out

Is anyone know what the problem is? How to solve it?

Thanks in advance!