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Design matrix and contrast

Hello everyone,

I'd like to use ROAST for analysis of gene sets from "limma" package.

In its input, there is "design matrix" and contrast. Actually, I didn't understand what they are (I am not statistician). Does anyone know a good and simple reference about them?

Thanks.

gene-set-analysis limma roast

1 answer

I have found some useful stuff here.

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