Postdoctoral Position in Computational and Systems Biology of Pathogen Drug Resistance
The Ferdig lab, in The Eck Institute for Global Health and the Department of Biological Sciences at the University of Notre Dame, is seeking a computational biologist with interest in network-based inference and large-scale data integration. The fellow will work both independently and as part of a collaborative team using whole-genome approaches to study drug targets and drug resistance evolution in the malaria parasite, Plasmodium falciparum.
A range of available projects includes: (1) Characterization and mining of transcript and regulatory networks of drug resistant parasites; (2) Systems genetics, using segregating parasite populations and mutant parasite libraries along with genome-scale data to connect genotypes to phenotypes; and (3) Integration of newly generated and existing public data to find drug targets, map chemical/cellular space not currently exploited by drugs and to predict effective drug combinations.
To align with these projects, the candidate should have a strong working knowledge of cellular mechanisms and biological pathways along with interest/expertise in one or more of the following:
- Regulation of gene expression; network analytical methods and data mining; accessing and integrating data resources; evolutionary genomics
- Mining of biological information, including transcript data from both microarrays and RNAseq; machine learning; skills in scripting languages such as Python, Perl, Matlab, or R.
The position is designed to ensure a strong training trajectory for a computational scientist aspiring to an independent research career. This includes a rich opportunity to interface with other quantitative/computational/evolutionary biologists across campus, including the Interdisciplinary Center for Network Science Applications (iCeNSA), along with collaborators at other institutions. Salary will be at standard levels per NIH and institutional guidelines.
Submit a current C.V. and names of 3 references to Dr. Michael Ferdig, Professor, Department of Biological Sciences, University of Notre Dame, IN 46556-0369, ferdig.1@nd.edu (574) 631-9973.
The Eck Institute for Global Health (EIGH) is a university-wide institution that recognizes health as a fundamental human right and endeavors to promote research, training, and service to advance health standards for all people, especially people in low- and middle-income countries who are disproportionately impacted by preventable diseases.
The University of Notre Dame is an Affirmative Action/Equal Opportunity Employer. Women and minority candidates are encouraged to apply.
