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Program to find genes up/down-regulated by a given gene

Hi,

I wanted to know if there is any program available that can take my gene of interest as input and give me the genes that are up/down-regulated by it.

Any help would be highly appreciated.

geo upregulated gene downregulated
• 3,369 views • link
updated by Ram Ram • written by c_u c_u

also, does anyone think 'Expression Atlas' does this?

• 1 views • link
written by c_u c_u

2 answers

I guess you can look at KEGG, probably at programmatic queries to it. How I wish we had such a resource though!

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written by Ram Ram

Thanks Ram for the quick reply. I'll have a look. Actually I am planning to do this as my Masters thesis - making this tool.

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written by c_u c_u

I look forward to seeing a working prototype!

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written by Ram Ram

Hey man, the internet gods send me here. Did you do it ?

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written by hugo.avila hugo.avila

(Sorry, i replied to the wrong person.) Hey man, the internet gods send me here. Did you do it ?

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written by hugo.avila hugo.avila

Hey hugo, yes! And we are planning to publish it early next year. Will upload a preprint soon and will post the link here

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written by c_u c_u

That's very cool ! I'll be wating ;)

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written by hugo.avila hugo.avila

Beside KEGG, you can also look at WikiPathways and Reactome. Moreover, Cytoscape offers some plugins for regulation network and pathways analysis.

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updated by Ram Ram • written by alesssia alesssia

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