Hello,
I am trying to analyze lnkRNA results from RNA-seq. Uploading lnkRNA gene names into DAVID, but it does not recognize most of them. The gene names look like this: AC000068.5; AP001625.4.
Any suggestions how to sort out the problem with DAVID, and also what else one can do with this type of data?
Thanks!
1 answer
Current functional annotations only cover protein_coding genes. Only consider protein_coding genes when you do functional analysis (Gene Ontology or KEGG).
First RNA you mentioned is Antisense:
Second one: Novel Intronic
If you need information about LncRNAs, you can have a look into these available databases: (Information about functional annotation for LncRNAs are limited for now)
- http://www.lncipedia.org/
- http://www.lncrnadb.org/
- http://bioinfo.life.hust.edu.cn/lncRNASNP/
- http://lncrna.big.ac.cn/index.php/Main_Page
- http://www.lncrna2target.org/
JFI: You can also use GeneSCF tool which clusters all protein_coding genes based on functions (GeneOntology, KEGG and reactome) and gives detailed results for protein coding genes (Including statistics):
Gene Set Clustering based on Functional annotation (GeneSCF)
Update GeneSCF v1.1: Support for more organisms and for information please follow http://genescf.kandurilab.org/
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