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how to identify that one gene have similar intensity value as other genes in the samples

please help me with this question

how one might take microarray intensity values calculated from
5 samples, and identify which genes have similar intensity values across all 5 samples. Assume that the
samples are collected at regular intervals during a process being studied, with the first sample from
day 0, the second sample from day 1, etc. Also, assume there is a separate probe on the microarray
for each gene

thanks alot guys!

microarray intensity value
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updated by Ram Ram • written by kimberly • kimberly

1 answer

Yanai et al. defines a Tau index for tissue specificity T = (sum (1-intensity/max(intensity) ) / (N-1). It actually works quite well.

In your case you are looking for probes with a tau index near zero, indicating that they have equal expression values across all samples.

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updated by Ram Ram • written by David Westergaard David Westergaard

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