How to visualize the similarity between transcriptome expression in different conditions in one heatmap ?
Hi,
I have transcriptome expression profile of an organism with some biological replicates in different conditions. I want to visualize the transcriptome expression similarity in different conditions in one heatmap.
Does anyone have idea how can I do that ? which metrics should I compute?
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Check Cummerbund. I think it does what you want.
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Maybe unrelated to your question but you could get better sample relations using the package 'supraHex'. See demo: http://supfam.org/supraHex/demo-Fang.html
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See links here: How To Draw A Heat Map For Gene Expression Data?
http://www2.warwick.ac.uk/fac/sci/moac/people/students/peter_cock/r/heatmap/
you will need to compute pearson correlation and plot with heatmap.2
See code here: https://github.com/crazyhottommy/NGS-scripts/blob/master/DESeq_MCF7_hypoxia_RNA-seq.r