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What'S The Difference Between Trimming In Phred And Phrap?

I saw there are trimming options in both phred and phrap. I wonder what is the difference? And is there a general recommendation about whether and how to use trimming with phred phrap?

trimming

1 answer

Just glanced over the docs, looks like phred trimming is primarily based on base qualities, while phrap allows input of un-trimmed sequences and then decide whether to trim based not only on low qualities at ends and assembly situations. I think people that are more familiar with this assembly pipeline will give you a more definite answer.

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