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gene (or SNP) related to a disease

Is there an authoritative database to find which genes (SNPs) are already known for which disease? With no limit on the study method. Thanks! (New to biology)

gwas snp disease
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updated by Ram Ram • written by yliueagle yliueagle

4 answers

Have a look at DisGeNET. It is a very well done and well supported database that aggregates and curates information from other sources. We are happy to use it in Open PHACTS (which also offers another way to access it).

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updated by Ram Ram • written by Chris Evelo Chris Evelo

Thanks for advising

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written by yliueagle yliueagle

The GWAS catalogue might be worth a look. Otherwise ClinVar.

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updated by Ram Ram • written by Emily Emily

Thanks for your advice. I am trying it.

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written by yliueagle yliueagle

A database of interest is GRASP.

GRASP v1.0 contains >6.2 million SNP-phenotype association from among 1390 GWAS studies. The authors re-annotated GWAS results with 16 annotation sources including some rarely compared to GWAS results (e.g. RNAediting sites, lincRNAs, PTMs).

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updated by Ram Ram • written by Sean Davis Sean Davis

Thanks for your advice.

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written by yliueagle yliueagle
Clinvar and biobase can be useful too.
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written by always_learning always_learning

I assume by BioBase you mean HGMD? BioBase are now owned by Qiagen. The public HGMD resource is here: http://www.hgmd.org/

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updated by Ram Ram • written by User 59 User 59

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