This is a test version of Biostars. For the public version, visit https://www.biostars.org.
how to select candidate genes after resequencing

Hi, I am now doing some researches of resequencing. Now I've got a large amount of SNPs, and want to utilize them to identify candidate genes. But I am very confused of it. How can I select these candidate genes? With the help of Ensemble or David, or any other tools?

snp sequence
• 2,870 views • link
updated by Ram Ram • written by jane.zh • jane.zh

You need to elaborate your question or make it more clear. I quiet didn't get what you want to do?

• 0 views • link
written by Ashutosh Pandey Ashutosh Pandey

I want to find positive select sweep, and locate some genes which participate in this positive selection. I've konown positons of SNPs, and I want to find those important genes through the information of these SNPs.

• 0 views • link
written by jane.zh • jane.zh

2 answers

The Variant Effect Predictor will tell you what genes your variants hit and what effect they have on them.

• 0 views • link
written by Emily Emily

You could verify if your SNPs have potential deleteriousness effect with CADD (Combined Annotation Dependent Depletion) and choose the genes with the most probable deleterious SNPs.

• 0 views • link
updated by Ram Ram • written by Maxime Lamontagne Maxime Lamontagne

Log in to answer this question.

More posts like this