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How to generate LOH file with aCGH data?

Hi everyone,

I have several tumours with array CGH data. I would be interested in determining which regions are subjected to LOH. I have two questions:

  1. How would I go about generating a LOH file for my samples?
  2. Would the file indicate regions subjected to LOH overall or for each sample?

Thank you!

loss-of-heterozygosity

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