Based on this How To Generate Mutations In Sequences Of A Fasta File?, I found EMBOSS program which helped to mutated a protein. However, this tool only mutates randomly. I would like to have a tool or a script which help me mutate at a specific point in the protein. Can you list some for me? Thank you.
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ganuongphap •
Do you mean a tool that would predict the effect of a mutated site?
If so, are you referring to structural implications, or just predicted deleteriousness?
If you just want to check whether a given variant is likely to be damaging? If you mean that, you might try CADD: http://cadd.gs.washington.edu/
Hope that helps.
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fadsfadfdsafdasfdsa
After looking its website, I think this tool is for gene mutation, not protein mutation. I'm studying in protein, not gene.
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That's easy enough to do by hand that I doubt anyone has bothered. You could also trivially do that with biopython or bioperl.
Hi,
check my scripts at : http://bo-protscience.fr/peaccel/Mutagenesis.html
Bernard
Your tool is great! Is it possible to download it?