what is stem loop in miRNA at miRBase data base?
Hi all,
I'm searching for the miRNAs in miRBase database. when I enter the ID of miRNA, I get following information:
Accession number MIMAT0000062
ID hsa-let-7a-5p
Previous IDs hsa-let-7a
Sequence ugagguaguagguuguauaguu
Get sequence
Stem-Loop hsa-let-7a-1 hsa-let-7a-2 hsa-let-7a-3
I want to figure out, what is the Stem-loop and is it functional inside of cell?
EDIT on 9/23/2021 by @Ram:
Removed the links from the code block above and added them here:
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Have you tried looking it up on google or pubmed? Even wikipedia describes what a stem-loop is.
I see, it's pre-miRNA IDs. right?
You may find this blog post from miRBase informative.
Great link, I always wondered about those names.
@Devon Ryan, what is the relationship between expression level of miRNA precursor and mature miRNA ? becuase I just have information about the targeting of mature miRNA from TargetScan and on other hand I need the expression level of these miRNAs which I got from TCGA. but all miRNA IDs in TCGA are miRNA precursor IDs. How can I solve this problem ?