Predict effect of pH on enzymatic activity

Hi all,

I was wondering... given the 3D structure of an enzyme, is it possible to predict the effect of pH on its catalytic activity? Are there user-friendly tools that allow me to do so?

Thanks!

• 3,146 views • link

updated 9.8 years ago by Biostar

• written 12.3 years ago by miquelduranfrigola

1 answer

Check if this method can serve your purpose. There is an online server for Thematics

THEMATICS: A simple computational predictor of enzyme function from structure

• 0 views • link

updated 6.6 years ago by Ram

• written 12.3 years ago by Woa

More posts like this

protein interaction prediction
written 11 months ago by Fatemeh •

Hi everyone, I am wondering if there is a possibility to predict the protein interactions and finding possible targets for an specific protein of interest …
How to analysis mutations effects bioinformatically?
written 7.8 years ago by Yoosef •

Hello In a rare syndrome, we have identified there mutations in a family. We want to bioinformatically analyses these mutations. We need to know are …
Methods for integrating in vitro information to predict enzyme activity
written 8.2 years ago by superaude •

Our group has measured Kcat on a WT enzyme and 28 single-AA substitution variants. How would one go about using this information to predict the …
db with effect of SNP on gene or regulatory region
written 8.9 years ago by theoharis •

Im looking for a database where a SNPs effect on the gene or regulatory region its in is stated. For example if its in a …
3d modeling of protein
written 10.3 years ago by Ehsan •

i want to predict the **3d (tertiary) structure** of a hypothetical protein **without using homology modeling**. suggest me any **softwere/online tool** that i can use …
Mutational Effects In Trna
written 12.4 years ago by Raghul

Hi It was easy to learn the possible mutational effects for protein with so much literature available. My case becomes difficult as it happens in …
Calculating Units Of Enzyme Activity
written 12.9 years ago by Caitlin

Hi all. Note: This is not a homework question. I am studying for an exam. I'm preparing for an exam in my biotechnology class and …
Predicting Effect Of Mutations In Terms Of Activity
written 13.6 years ago by Pappu

I have a membrane protein (~400 aa) in which >90% of the mutations result in the loss of activity. I was trying to use SVM …
Types Of Bioinformatics Analysis To Perform On A Given Sequence
written 14.9 years ago by Ssh3 •

Hi, I am new to Bioinformatics. I was given a sequence of a protein (no 3D structure available) to perform bioinformatics analysis on it. What …
Enzyme Thermostability Vs Activity
written 15.3 years ago by User 1933 •

Thermo stability is measured by Differential Scanning Calorimetry and different enzyme assays can be used to measure enzyme activity, say by measuring quantity of enzyme …