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Forum: Am I Way Out of My league? Early Career and realistic job prospects

Hi everyone,

I'm looking for some honest advice from people currently working in bioinformatics or computational biology. I'm trying to figure out whether I'm realistically competitive for entry-level bioinformatics positions or whether I need significantly more training before applying. I have no real experience outside of school. Should I sign up for Codecademy or DataCamp?

My background:

I recently completed a B.S. in Biological Sciences from Arizona State University, with a focus on computational life sciences. I also completed/earned training through ASU's Computational Life Sciences certificate, which has given me exposure to:

R statistical analysis data analysis and visualization Python/computing for research functional genomics biological datasets basic computational approaches to biological research

I also currently work in a laboratory/diagnostic environment at Quest Diagnostics, so I have professional laboratory experience, although my current position is not a bioinformatics role.

My goal is to transition from traditional laboratory work into bioinformatics, computational biology, or biological data analysis. I am also planning to pursue a master's degree in Computational Life Sciences, but I would ideally like to begin gaining relevant professional experience rather than waiting until I finish the master's.

Where I'm struggling is understanding how employers actually view someone with my background...

bachelorsdegree earlycareer

3 answers

I don't think I can give you a lot of insight into how employers see your background, but I also had a non-traditional journey until I started working as a bioinformatician. A few things that I have found helpful were:

  1. UCSD's Bioinformatics specialization on Coursera (you can also get the textbook to self-learn if you don't want to go through the course, and it's a great resource for bottom-up learning and reasoning through comp. bio algorithms);
  2. independent projects that you take on to explore different techniques;
  3. reading and keeping up with papers in fields of interest; and
  4. staying flexible when it comes to opportunities.

You mentioned that you're working right now on diagnostics/wet-lab side. As you learn and build pipelines/workflows or implement analyses in side projects, you could try expressing to your manager your willingness and ability to do the analyses as well, if that's possible. If not, there can also be freelance, contract, or part-time positions at labs where you can gain experience as a recent grad.

Not withstanding that the job market itself is just not in a nice place at the moment, I don't think you need to do a lot more necessarily to access an entry level role.

As an employer, I would more often than not be looking at PhD-level graduates and above, but that is for roles that are not really entry level per se, where we're expecting the invidual to hit the ground running a bit more.

The beauty of coding based roles is you are likely to be judged more on your skills and portfolio than on your academics specifically. You can bolster your CV in your own time by doing small analytical projects, and building a strong Github profile.

I am also planning to pursue a master's degree in Computational Life Sciences, but I would ideally like to begin gaining relevant professional experience rather than waiting until I finish the master's.

If doing a master's, you should really find one that leans heavily into thesis or practicum-based work to garner real experience. Look into summer or year-long internships.

While I am biased, my institution (St. Jude Children's Research Hospital) provides many excellent opportunities for both internships and a new master's program in Applied Biomedical Data Sciences (all paid). Other such programs exist elsewhere throughout the US as well.

Frankly, the bar for entry is getting ever higher, and you really need to be able to point to things you've actually meaningfully contributed to - listing a vague set of skills just isn't going to cut it. The job market is rough, and you need to be able to set yourself apart to get a foothold.

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