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How to quickly make a surjection between Minigraph graph and MC graph in HPRC

I am now using HPRC v2.0 data and there is two kind of graph. One is build by MC and contains many littile node while the other is build by Minigraph (sv.gfa format). The graph build by Minigraph do not contain haplotype path. I want to connect this two graph together since I only focus on SV. I want to know which nodes make up each SV node. Is there any faster way to solve it?

vg

1 answer

I don't think you can "connect" these completely different graphs together. Please read up on the theory behind the very different GFA and rGFA approaches to pangenome graphs here

https://github.com/colindaven/awesome-pangenomes

Especially check the blog post linked on that page.

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