Can you compare GETx and TCGA miRNA non normalized counts a
Hi,
Is it possible to compare TCGA miRNA non-normalized counts read with GETx miRNA counts read? How do you batch correct in this case, and is that enough to remove technical bias?
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ATpoint
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radwa_noreen •
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radwa_noreen •
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This was asked dozens of times before, please searh for previous threads. In brief, batch is nested with condition, so actually it's not possible to correct for anything. Then however this paper (https://www.nature.com/articles/sdata201861) is always cited when people need a justification to still attempt some correction. Read it, see whether you find it convincing, and if so, consider doing the same.
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