With the current availability of bioinformatics and genetic data, would it be possible to find out what specific biochemical pathway is associated with a given species?

For instance, would it be possible to determine what biochemical pathways are specific for, say, E. coli, in comparison to Enterococcus? Of course, there is a lot of data; let's focus on the quorum-sensing pathway. Using the KEGG database, for instance, it is possible to get the visualization of the pathways for E. coli:

as well as for Enterococcus:

Is there a way to determine what of these pathways are different between these two species? Maybe a specific bioinformatic tool or a different database than KEGG?

Thank you.